UK U-turn on Alzheimer’s Medication

Thousands of UK Alzheimer’s sufferers could now get drug treatments following a turnabout by a health watchdog.

The National Institute for Health and Clinical Excellence (NICE) now says that evidence supports the use of drugs for “mild” symptoms.

Currently rules prevent NHS doctors from prescribing donepezil, galatamine and rivastigmine in the early stages of Alzheimer’s disease.  Many health professionals have been campaigning for the use of early drug treatment to help dementia patients, and it is felt that this new guidance heralds a “momentous day” in the care of Alzheimer’s.

The availability of early drug treatment with the medication mentioned above has caused controversy for almost ten years in the UK.  In 2005 NICE ruled that the drugs should not be available on the NHS.  A year later they reviewed their ruling, stating that the drugs could be made available for patients with “moderate” symptoms, but still ruled that they should not be provided for “mild” sufferers.

The formula that NICE had used to calculate the “value for money” for the NHS to offer the drugs was then subject to a court case.  Following the disclosure of their economic model, in 2009 NICE had to admit “technical inaccuracies” in the model and amend it. 

Now the CEO of NICE, Sir Andrew Dillon, is quoted as saying "Clinical trials have continued to show the positive effect of these drugs.  Our increased confidence in the benefits and costs associated with the use of the three drugs for treating mild and moderate stages of the disease has enabled us to make positive recommendation for their use in mild disease."

The Alzheimer’s Society have stated that the u-turn marks a “momentous day”, with approximately half of the 62,000 people who develop the disease each year being able to benefit from these drugs.  The medication, which costs roughly £2.80 per person per day is not a “miracle cure”, but certainly can enhance quality of life. 
Ruth Sutherland of the Alzheimer’s Society sums it up as "For the price of a cup of coffee they can mean the difference between recognising your loved ones and playing with your grandchildren.”

The drugs do not always work for everyone but there will be thousands of old people starting with symptoms of dementia that will now benefit with the extra support for memory, concentration and attention span that these drugs offer.


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